What Is The Pathophysiology Of Bacterial Meningitis?

The most common cause of meningeal inflammation is bacterial or viral infection. (See Etiology.) Bacterial meningitis consists of pyogenic inflammation of the meninges and the underlying subarachnoid CSF. If not treated, it may lead to lifelong disability or death.

What is the pathophysiology of meningitis?

Pathogenesis. The organisms that cause bacterial meningitis colonize the nasopharynx and, from there, they get into the blood stream. They enter the subarachnoid space by passing through endothelial cells (transcytosis), getting across the porous choroid plexus capillaries, or being carried by granulocytes.

how Bacterial Meningitis affects the body? Meningitis is an infection that causes the protective membranes of the nervous system to swell. Inflammation of the brain and spinal cord can affect every part of your body. Swelling in the brain can also interfere with the senses. It can cause ringing in the ears (tinnitus), partial hearing loss, or deafness.

how does bacterial meningitis work?

Bacterial meningitis occurs when these bacteria get in your bloodstream and travel to your brain and spinal cord to start an infection. Most bacteria that cause this form of infection are spread through close personal contact, such as: coughing. sneezing.

What is acute bacterial meningitis?

Acute bacterial meningitis is rapidly developing inflammation of the layers of tissue that cover the brain and spinal cord (meninges) and of the fluid-filled space between the meninges (subarachnoid space) when it is caused by bacteria.

What is the pathophysiology of a disease?

Pathophysiology is the study of the changes of normal mechanical, physical, and biochemical functions, either caused by a disease or resulting from an abnormal syndrome. From: Haematology Case Studies with Blood Cell Morphology and Pathophysiology, 2017.

What are the complication of meningitis?

Some of the most common complications associated with meningitis are: hearing loss, which may be partial or total – people who have had meningitis will usually have a hearing test after a few weeks to check for any problems. recurrent seizures (epilepsy) problems with memory and concentration.

Where is bacterial meningitis found?

The bacteria most often responsible for bacterial meningitis are common in the environment and can also be found in your nose and respiratory system without causing any harm. Sometimes meningitis occurs for no known reason.

What type of antibiotics are used to treat meningitis?

Commonly used meningitis treatments include a class of antibiotics called cephalosporins, especially Claforan (cefotaxime) and Rocephin (ceftriaxone). Various penicillin-type antibiotics, aminoglycoside drugs such as gentamicin, and others, are also used.

What is the survival rate of bacterial meningitis?

One large study of adults with community-acquired bacterial meningitis reported an overall mortality rate of 21%, including a 30% mortality rate associated with Streptococcus pneumoniae meningitis and a 7% mortality rate for Neisseria meningitidis (2). In adults, the most commonly identified organisms are S.

Can meningitis be cured?

Bacterial meningitis requires immediate hospitalization. Early diagnosis and treatment will prevent brain damage and death. Bacterial meningitis is treated with intravenous antibiotics. Viral meningitis may resolve on its own, but some causes of viral meningitis will be treated with intravenous antiviral medications.

What is the difference between meningitis and encephalitis?

Meningitis is an infection of the meninges, the membranes that surround the brain and spinal cord. Encephalitis is inflammation of the brain itself.

What causes fungal meningitis?

Fungal meningitis is rare and usually the result of spread of a fungus through blood to the spinal cord. Although anyone can get fungal meningitis, people with weakened immune systems, like those with HIV infection or cancer, are at higher risk.

How long does it take to recover from bacterial meningitis?

Bacterial meningitis often requires hospitalization and treatment with antibiotics for one to two weeks. Although this infection is very serious, many patients can make a full recovery if it’s treated right away.

What are significant signs of acute bacterial meningitis?

Acute Bacterial Meningitis. Acute bacterial meningitis is rapidly progressive bacterial infection of the meninges and subarachnoid space. Findings typically include headache, fever, and nuchal rigidity. Diagnosis is by cerebrospinal fluid (CSF) analysis.

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